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Neuropsychiatric syndrome in Systemic Erythematous Lupus

NOTE: Translated using software of translation of Spanish to English

Abstract

Neuropsychiatric Systemic Lupus Erythematosus (NP-SLE) is a syndrome with a wide range of multiple clinical presentations. At
the present time, we can define it with 19 different types. The clinical incidence of NP-SLE is 25% in the patients with SLE. The diagnosis
is based on clinical suspicion, accurate differential diagnosis, neuroimaging studies (CT scan, MRI and MRA). The serologic support is
based on antibodies like antiribosomal P, lupus anticoagulant and anticardiolipines. Treatment consists in corticoids and, in some cases
as rescue agents, immunomodulators like intravenous cyclophosphamide and plasmapheresis. We present a clinical case which permits
discussion of what is mentioned above.
Key words: Lupus, SLE, Neuropsychiatric lupus, Vasculitis.

 

Author: Ecuadorian magazine of neurology

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