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Articles for Doctors
Gliosarcomas
Cerebral:
Inmunohistoquímicos
Clinical-Surgical
aspects, Correlation
with Studies of
Neurograph, Findings
and Prognosis
NOTE: Translated
using software of
translation of
Spanish to English
ABSTRACT: Gliosarcomas are maling, rare, and dimorphic neoplasms
formed by glioblastoma associated with sarcomatous components that may develop from the
malignant transformation of hyperplastic vascular elements. We report three patients with
gliosarcoma to analyze the correlation between neuroimaging and surgical findings, and
prognosis. Clinical manifestations had a sudden onset, in previously healthy patients, and
was characterized by a syndrome of intracranial hypertension of acute onset related to the
development of an intratumoral hemorrhage. In two of our patients the tumors were observed
as intra-axial lesions having large areas of necrosis and peripheral enhancement of
contrast material. This finding is similar to that observed in patients with
glioblastomas. The other patient presented with a well-defined and homogeneous hyperdense
lesion the resembled a meningioma. In our series the patients with the longest survival
was the one who had a lesion resembling a meningioma, in whom the sarcomatous component of
the lesion predominated.
Author:
Ecuadorian
magazine of neurology
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